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Cell-based inhibitor screening identifies multiple protein kinases important for circadian clock oscillations

Molecular oscillation of the circadian clock is based on E-box-mediated transcriptional feedback loop formed with clock genes and their encoding products, clock proteins. The clock proteins are regulated by post-translational modifications such as phosphorylation. We investigated the effects of a se...

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Detalles Bibliográficos
Autores principales: Kon, Naohiro, Sugiyama, Yasunori, Yoshitane, Hikari, Kameshita, Isamu, Fukada, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594307/
https://www.ncbi.nlm.nih.gov/pubmed/26478783
http://dx.doi.org/10.4161/19420889.2014.982405