Domain III S4 in closed-state fast inactivation: Insights from a periodic paralysis mutation

Heterologous expression of sodium channel mutations in hypokalemic periodic paralysis reveals 2 variants on channel dysfunction. Charge-reducing mutations of voltage sensing S4 arginine residues alter channel gating as typically studied with expression in mammalian cells. These mutations also produc...

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Detalles Bibliográficos
Autores principales: Groome, James R, Jurkat-Rott, Karin, Lehmann-Horn, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Article Addenda
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594372/
https://www.ncbi.nlm.nih.gov/pubmed/25483590
http://dx.doi.org/10.4161/19336950.2014.958924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594372/
https://www.ncbi.nlm.nih.gov/pubmed/25483590
http://dx.doi.org/10.4161/19336950.2014.958924

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