Insights into the structural nature of the transition state in the Kir channel gating pathway

In a previous study we identified an extensive gating network within the inwardly rectifying Kir1.1 (ROMK) channel by combining systematic scanning mutagenesis and functional analysis with structural models of the channel in the closed, pre-open and open states. This extensive network appeared to st...

Descripción completa

Detalles Bibliográficos
Autores principales: Fowler, Philip W, Bollepalli, Murali K, Rapedius, Markus, Nematian-Ardestani, Ehsan, Shang, Lijun, Sansom, Mark SP, Tucker, Stephen J, Baukrowitz, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Article Addenda
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594414/
https://www.ncbi.nlm.nih.gov/pubmed/25483285
http://dx.doi.org/10.4161/19336950.2014.962371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594414/
https://www.ncbi.nlm.nih.gov/pubmed/25483285
http://dx.doi.org/10.4161/19336950.2014.962371

Ejemplares similares