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Drosophila models reveal novel insights into mechanisms underlying neurodegeneration
The SAGA chromatin modifying complex functions as a transcriptional coactivator for a large number of genes, and SAGA dysfunction has been linked to carcinogenesis and neurodegenerative disease. The protein complex is comprised of approximately 20 subunits, arranged in a modular fashion, and include...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594482/ https://www.ncbi.nlm.nih.gov/pubmed/25483136 http://dx.doi.org/10.4161/19336934.2014.969150 |