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Drosophila models reveal novel insights into mechanisms underlying neurodegeneration

The SAGA chromatin modifying complex functions as a transcriptional coactivator for a large number of genes, and SAGA dysfunction has been linked to carcinogenesis and neurodegenerative disease. The protein complex is comprised of approximately 20 subunits, arranged in a modular fashion, and include...

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Detalles Bibliográficos
Autores principales: Mohan, Ryan D, Workman, Jerry L, Abmayr, Susan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594482/
https://www.ncbi.nlm.nih.gov/pubmed/25483136
http://dx.doi.org/10.4161/19336934.2014.969150