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mVps45 knockdown selectively modulates VAMP expression in 3T3-L1 adipocytes

Insulin stimulates the delivery of glucose transporter-4 (GLUT4)-containing vesicles to the surface of adipocytes. Depletion of the Sec1/Munc18 protein mVps45 significantly abrogates insulin-stimulated glucose transport and GLUT4 translocation. Here we show that depletion of mVps45 selectively reduc...

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Detalles Bibliográficos
Autores principales: Sadler, Jessica B A, Roccisana, Jennifer, Virolainen, Minttu, Bryant, Nia J, Gould, Gwyn W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594494/
https://www.ncbi.nlm.nih.gov/pubmed/26479872
http://dx.doi.org/10.1080/19420889.2015.1026494