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Lipid disequilibrium in biological membranes, a possible pathway to neurodegeneration
We recently reported that knocking down the enzyme phosphatidylserine decarboxylase, which synthesizes the phospholipid phosphatidylethanolamine (PE) in mitochondria, perturbs the homeostasis of the human Parkinson disease (PD) protein α-synuclein (expressed in yeast or worms). In yeast, low PE in t...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594524/ https://www.ncbi.nlm.nih.gov/pubmed/26480301 http://dx.doi.org/10.4161/19420889.2014.993266 |