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Bone marrow-derived mesenchymal stem cells enhance autophagy via PI3K/AKT signalling to reduce the severity of ischaemia/reperfusion-induced lung injury

Autophagy, a type II programmed cell death, is essential for cell survival under stress, e.g. lung injury, and bone marrow-derived mesenchymal stem cells (BM-MSCs) have great potential for cell therapy. However, the mechanisms underlying the BM-MSC activation of autophagy to provide a therapeutic ef...

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Detalles Bibliográficos
Autores principales: Li, Jing, Zhou, Jian, Zhang, Dan, Song, Yuanlin, She, Jun, Bai, Chunxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594676/
https://www.ncbi.nlm.nih.gov/pubmed/26177266
http://dx.doi.org/10.1111/jcmm.12638