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Periostin down-regulation attenuates the pro-fibrogenic response of hepatic stellate cells induced by TGF-β1

Liver fibrosis is characterized by an exacerbated accumulation of deposition of the extracellular matrix (ECM), and the activation of hepatic stellate cells (HSC) plays a pivotal role in the development of liver fibrosis. Periostin has been shown to regulate cell adhesion, proliferation, migration a...

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Detalles Bibliográficos
Autores principales: Hong, Li, Shejiao, Dai, Fenrong, Chen, Gang, Zhao, Lei, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594687/
https://www.ncbi.nlm.nih.gov/pubmed/26249143
http://dx.doi.org/10.1111/jcmm.12636