Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis

In humans, mutations in ATGL lead to TG accumulation in LDs of most tissues and cells, including peripheral blood leukocytes. This pathologic condition is called Jordans’ anomaly, in which functional consequences have not been investigated. In the present study, we tested the hypothesis that ATGL pl...

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Detalles Bibliográficos
Autores principales: Schlager, Stefanie, Goeritzer, Madeleine, Jandl, Katharina, Frei, Robert, Vujic, Nemanja, Kolb, Dagmar, Strohmaier, Heimo, Dorow, Juliane, Eichmann, Thomas O., Rosenberger, Angelika, Wölfler, Albert, Lass, Achim, Kershaw, Erin E., Ceglarek, Uta, Dichlberger, Andrea, Heinemann, Akos, Kratky, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Leukocyte Biology 2015
Materias:
Inflammation, Extracellular Mediators, & Effector Molecules
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594763/
https://www.ncbi.nlm.nih.gov/pubmed/26109679
http://dx.doi.org/10.1189/jlb.3A0515-206R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594763/
https://www.ncbi.nlm.nih.gov/pubmed/26109679
http://dx.doi.org/10.1189/jlb.3A0515-206R

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