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Cooperative and independent functions of FGF and Wnt signaling during early inner ear development

BACKGROUND: In multiple vertebrate organisms, including chick, Xenopus, and zebrafish, Fibroblast Growth Factor (FGF) and Wnt signaling cooperate during formation of the otic placode. However, in the mouse, although FGF signaling induces Wnt8a expression during induction of the otic placode, it is u...

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Detalles Bibliográficos
Autores principales: Wright, Kevin D., Mahoney Rogers, Amanda A., Zhang, Jian, Shim, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594887/
https://www.ncbi.nlm.nih.gov/pubmed/26443994
http://dx.doi.org/10.1186/s12861-015-0083-8