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Downregulation of ASPP2 in pancreatic cancer cells contributes to increased resistance to gemcitabine through autophagy activation

BACKGROUND: Apoptosis-stimulating of p53 protein 2 (ASPP2) is one of the ASPP family members and it has been reported to be associated with human cancer. However, the role of it in pancreatic cancer is still not clear. METHODS: We analyzed the expression level of ASPP2 in cancer tissue samples with...

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Detalles Bibliográficos
Autores principales: Song, Bin, Bian, Qi, Zhang, Yi-Jie, Shao, Cheng-Hao, Li, Gang, Liu, An-An, Jing, Wei, Liu, Rui, Zhou, Ying-Qi, Jin, Gang, Hu, Xian-Gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594892/
https://www.ncbi.nlm.nih.gov/pubmed/26438046
http://dx.doi.org/10.1186/s12943-015-0447-5