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High Endogenous Expression of Chitinase 3-Like 1 and Excessive Epithelial Proliferation with Colonic Tumor Formation in MOLF/EiJ Mice

Colorectal cancer (CRC) development is mediated by uncontrolled survival and proliferation of tumor progenitor cells. Using animal models to identify and study host-derived factors that underlie this process can aid interventions in preventing tumor expansion and metastasis. In healthy steady states...

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Detalles Bibliográficos
Autores principales: Low, Daren, DeGruttola, Arianna K., Poltrak, Alexander, Mizoguchi, Atsushi, Mino-Kenudson, Mari, Mizoguchi, Emiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594921/
https://www.ncbi.nlm.nih.gov/pubmed/26440614
http://dx.doi.org/10.1371/journal.pone.0139149