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Basigin-mediated redistribution of CD98 promotes cell spreading and tumorigenicity in hepatocellular carcinoma

BACKGROUND: Dysregulated endocytosis of membrane proteins contributes significantly to several hallmarks of cancer. Basigin can enhance cancer progression, but its precise mechanism remains unclear. CD98 promotes cell spreading and tumorigenicity by triggering integrin clustering and enhancing cell...

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Detalles Bibliográficos
Autores principales: Wu, Bo, Wang, Yi, Yang, Xiang-Min, Xu, Bao-Qing, Feng, Fei, Wang, Bin, Liang, Qiang, Li, Yu, Zhou, Yang, Jiang, Jian-Li, Chen, Zhi-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594993/
https://www.ncbi.nlm.nih.gov/pubmed/26437640
http://dx.doi.org/10.1186/s13046-015-0226-6