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Genetic Variations in Pattern Recognition Receptor Loci Are Associated with Anti-TNF Response in Patients with Rheumatoid Arthritis

OBJECTIVES: To determine whether genetic variation within genes related to the Toll-like receptor, inflammasome and interferon-γ pathways contributes to the differences in treatment response to tumour necrosis factor inhibitors (anti-TNF) in patients with rheumatoid arthritis (RA). METHODS: In a ret...

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Detalles Bibliográficos
Autores principales: Sode, Jacob, Vogel, Ulla, Bank, Steffen, Andersen, Paal Skytt, Hetland, Merete Lund, Locht, Henning, Heegaard, Niels H. H., Andersen, Vibeke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595012/
https://www.ncbi.nlm.nih.gov/pubmed/26440629
http://dx.doi.org/10.1371/journal.pone.0139781