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H-Ferritin Is Preferentially Incorporated by Human Erythroid Cells through Transferrin Receptor 1 in a Threshold-Dependent Manner

Ferritin is an iron-storage protein composed of different ratios of 24 light (L) and heavy (H) subunits. The serum level of ferritin is a clinical marker of the body’s iron level. Transferrin receptor (TFR)1 is the receptor not only for transferrin but also for H-ferritin, but how it binds two diffe...

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Detalles Bibliográficos
Autores principales: Sakamoto, Soichiro, Kawabata, Hiroshi, Masuda, Taro, Uchiyama, Tatsuki, Mizumoto, Chisaki, Ohmori, Katsuyuki, Koeffler, H. Phillip, Kadowaki, Norimitsu, Takaori-Kondo, Akifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595017/
https://www.ncbi.nlm.nih.gov/pubmed/26441243
http://dx.doi.org/10.1371/journal.pone.0139915