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Metabolic reprogramming: the emerging concept and associated therapeutic strategies
Tumor tissue is composed of cancer cells and surrounding stromal cells with diverse genetic/epigenetic backgrounds, a situation known as intra-tumoral heterogeneity. Cancer cells are surrounded by a totally different microenvironment than that of normal cells; consequently, tumor cells must exhibit...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595070/ https://www.ncbi.nlm.nih.gov/pubmed/26445347 http://dx.doi.org/10.1186/s13046-015-0221-y |