Suppression of Dendritic Cell-Derived IL-12 by Endogenous Glucocorticoids Is Protective in LPS-Induced Sepsis

Sepsis, an exaggerated systemic inflammatory response, remains a major medical challenge. Both hyperinflammation and immunosuppression are implicated as causes of morbidity and mortality. Dendritic cell (DC) loss has been observed in septic patients and in experimental sepsis models, but the role of...

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Detalles Bibliográficos
Autores principales: Li, Caiyi C., Munitic, Ivana, Mittelstadt, Paul R., Castro, Ehydel, Ashwell, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595142/
https://www.ncbi.nlm.nih.gov/pubmed/26440998
http://dx.doi.org/10.1371/journal.pbio.1002269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595142/
https://www.ncbi.nlm.nih.gov/pubmed/26440998
http://dx.doi.org/10.1371/journal.pbio.1002269

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