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TGF-β1 Reduces miR-29a Expression to Promote Tumorigenicity and Metastasis of Cholangiocarcinoma by Targeting HDAC4

Transforming growth factor β1 (TGF-β1) and miRNAs play important roles in cholangiocarcinoma progression. In this study, miR-29a level was found significantly decreased in both cholangiocarcinoma tissues and tumor cell lines. TGF-β1 reduced miR-29a expression in tumor cell lines. Furthermore, anti-m...

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Detalles Bibliográficos
Autores principales: Wang, Huiling, Li, Caixia, Jian, Zhixiang, Ou, Yingliang, Ou, Jinrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595145/
https://www.ncbi.nlm.nih.gov/pubmed/26441331
http://dx.doi.org/10.1371/journal.pone.0136703