Endothelin-1 induces LIMK2-mediated programmed necrotic neuronal death independent of NOS activity

BACKGROUND: Recently, we have reported that LIM kinase 2 (LIMK2) involves programmed necrotic neuronal deaths induced by aberrant cyclin D1 expression following status epilepticus (SE). Up-regulation of LIMK2 expression induces neuronal necrosis by impairment of dynamin-related protein 1 (DRP1)-medi...

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Detalles Bibliográficos
Autores principales: Ko, Ah-Reum, Hyun, Hye-Won, Min, Su-Ji, Kim, Ji-Eun, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595180/
https://www.ncbi.nlm.nih.gov/pubmed/26438559
http://dx.doi.org/10.1186/s13041-015-0149-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595180/
https://www.ncbi.nlm.nih.gov/pubmed/26438559
http://dx.doi.org/10.1186/s13041-015-0149-3

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