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Quercetin reduces obesity-induced hepatosteatosis by enhancing mitochondrial oxidative metabolism via heme oxygenase-1

BACKGROUND: Obesity-induced hepatic lipid accumulation causes lipotoxicity, mitochondrial dysfunction, oxidative stress, and insulin resistance, and is implicated in non-alcoholic hepatic pathologies such as steatohepatitis and fibrosis. Heme oxygenase-1 (HO-1), an important antioxidant enzyme catal...

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Detalles Bibliográficos
Autores principales: Kim, Chu-Sook, Kwon, Yoonhee, Choe, Suck-Young, Hong, Sun-Myung, Yoo, Hoon, Goto, Tsuyoshi, Kawada, Teruo, Choi, Hye-Seon, Joe, Yeonsoo, Chung, Hun Taeg, Yu, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595266/
https://www.ncbi.nlm.nih.gov/pubmed/26445592
http://dx.doi.org/10.1186/s12986-015-0030-5