FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores

Mechanisms of adaptation to environmental changes in osmolarity are fundamental for cellular and organismal survival. Here we identify a novel osmotic stress resistance pathway in Caenorhabditis elegans (C. elegans), which is dependent on the metabolic master regulator 5’-AMP-activated protein kinas...

Descripción completa

Detalles Bibliográficos
Autores principales: Possik, Elite, Ajisebutu, Andrew, Manteghi, Sanaz, Gingras, Marie-Claude, Vijayaraghavan, Tarika, Flamand, Mathieu, Coull, Barry, Schmeisser, Kathrin, Duchaine, Thomas, van Steensel, Maurice, Hall, David H., Pause, Arnim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595296/
https://www.ncbi.nlm.nih.gov/pubmed/26439621
http://dx.doi.org/10.1371/journal.pgen.1005520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595296/
https://www.ncbi.nlm.nih.gov/pubmed/26439621
http://dx.doi.org/10.1371/journal.pgen.1005520

Ejemplares similares