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The effect of local variation in malaria transmission on the prevalence of sulfadoxine–pyrimethamine resistant haplotypes and selective sweep characteristics in Malawi

BACKGROUND: Persistence of sulfadoxine–pyrimethamine (SP) resistance has been described in an urban setting in Malawi where malaria transmission is relatively low. Higher malaria transmission is associated with greater genetic diversity and more frequent genetic recombination, which could lead to a...

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Detalles Bibliográficos
Autores principales: Artimovich, Elena, Kapito-Tembo, Atupele, Pensulo, Paul, Nyirenda, Osward, Brown, Sarah, Joshi, Sudhaunshu, Taylor, Terrie E., Mathanga, Don, Escalante, Ananias A., Laufer, Miriam K., Takala-Harrison, Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595317/
https://www.ncbi.nlm.nih.gov/pubmed/26437774
http://dx.doi.org/10.1186/s12936-015-0860-7