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Regulation of Connective Tissue Growth Factor and Cardiac Fibrosis by an SRF/MicroRNA-133a Axis

Myocardial fibrosis contributes to the remodeling of heart and the loss of cardiac function leading to heart failure. SRF is a transcription factor implicated in the regulation of a large variety of genes involved in cardiac structure and function. To investigate the impact of an SRF overexpression...

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Detalles Bibliográficos
Autores principales: Angelini, Aude, Li, Zhenlin, Mericskay, Mathias, Decaux, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595333/
https://www.ncbi.nlm.nih.gov/pubmed/26440278
http://dx.doi.org/10.1371/journal.pone.0139858