GIMAP5 Deficiency Is Associated with Increased AKT Activity in T Lymphocytes

Long-term survival of T lymphocytes in quiescent state is essential to maintain their cell numbers in secondary lymphoid organs. In mice and in rats, the loss of functional GTPase of the immune associated nucleotide binding protein 5 (GIMAP5) causes peripheral T lymphopenia due to spontaneous death...

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Detalles Bibliográficos
Autores principales: Chen, Xi-Lin, Serrano, Daniel, Mayhue, Marian, Hoebe, Kasper, Ilangumaran, Subburaj, Ramanathan, Sheela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595448/
https://www.ncbi.nlm.nih.gov/pubmed/26440416
http://dx.doi.org/10.1371/journal.pone.0139019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595448/
https://www.ncbi.nlm.nih.gov/pubmed/26440416
http://dx.doi.org/10.1371/journal.pone.0139019

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