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Hepatic veno-occlusive disease may develop in secondary iron overloaded mice after allogeneic hematopoietic stem cell transplantation with total body irradiation

BACKGROUND: The outcome of hematopoietic stem cell transplantation (HSCT) is poor in patients with secondary iron overload (SIO). We evaluated the relationship between SIO and veno-occlusive disease (VOD) in an animal model with radiation for HSCT. METHODS: We used a 6-week-old female BDF1 (H-2(b/d)...

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Detalles Bibliográficos
Autores principales: Yeom, Mi Young, Kim, Yoo Jin, Chung, Nack Gyun, Lee, Jae Wook, Jang, Pil Sang, Cho, Bin, Kye, Chul Seung, Jeong, Dae Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595579/
https://www.ncbi.nlm.nih.gov/pubmed/26457280
http://dx.doi.org/10.5045/br.2015.50.3.140