Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition

Lycorine is reported to be a multifunctional compound. We previously showed that lycorine is an HCV inhibitor with strong activity. Further research on the antivirus mechanism indicated that lycorine does not affect the enzymes that are indispensable to HCV replication but suppresses the expression...

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Detalles Bibliográficos
Autores principales: Chen, Duozhi, Cai, Jieyun, Cheng, Junjun, Jing, Chenxu, Yin, Junlin, Jiang, Jiandong, Peng, Zonggen, Hao, Xiaojiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595722/
https://www.ncbi.nlm.nih.gov/pubmed/26443922
http://dx.doi.org/10.1038/srep14972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595722/
https://www.ncbi.nlm.nih.gov/pubmed/26443922
http://dx.doi.org/10.1038/srep14972

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