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Genome-wide association study identifies new susceptibility loci for adolescent idiopathic scoliosis in Chinese girls

Adolescent idiopathic scoliosis (AIS) is a structural deformity of the spine affecting millions of children. As a complex disease, the genetic aetiology of AIS remains obscure. Here we report the results of a four-stage genome-wide association study (GWAS) conducted in a sample of 4,317 AIS patients...

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Detalles Bibliográficos
Autores principales: Zhu, Zezhang, Tang, Nelson Leung-Sang, Xu, Leilei, Qin, Xiaodong, Mao, Saihu, Song, Yueming, Liu, Limin, Li, Fangcai, Liu, Peng, Yi, Long, Chang, Jiang, Jiang, Long, Ng, Bobby Kin-Wah, Shi, Benlong, Zhang, Wen, Qiao, Jun, Sun, Xu, Qiu, Xusheng, Wang, Zhou, Wang, Fei, Xie, Dingding, Chen, Ling, Chen, Zhonghui, Jin, Mengran, Han, Xiao, Hu, Zongshan, Zhang, Zhen, Liu, Zhen, Zhu, Feng, Qian, Bang-ping, Yu, Yang, Wang, Bing, Lee, K. M., Lee, Wayne Y.W., Lam, T. P., Qiu, Yong, Cheng, Jack Chun-Yiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595747/
https://www.ncbi.nlm.nih.gov/pubmed/26394188
http://dx.doi.org/10.1038/ncomms9355