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Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum

Thiolase is the first enzyme catalysing the condensation of two acetyl-coenzyme A (CoA) molecules to form acetoacetyl-CoA in a dedicated pathway towards the biosynthesis of n-butanol, an important solvent and biofuel. Here we elucidate the crystal structure of Clostridium acetobutylicum thiolase (Ca...

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Detalles Bibliográficos
Autores principales: Kim, Sangwoo, Jang, Yu-Sin, Ha, Sung-Chul, Ahn, Jae-Woo, Kim, Eun-Jung, Hong Lim, Jae, Cho, Changhee, Shin Ryu, Yong, Kuk Lee, Sung, Lee, Sang Yup, Kim, Kyung-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595758/
https://www.ncbi.nlm.nih.gov/pubmed/26391388
http://dx.doi.org/10.1038/ncomms9410