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Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Thiolase is the first enzyme catalysing the condensation of two acetyl-coenzyme A (CoA) molecules to form acetoacetyl-CoA in a dedicated pathway towards the biosynthesis of n-butanol, an important solvent and biofuel. Here we elucidate the crystal structure of Clostridium acetobutylicum thiolase (Ca...
Autores principales: | Kim, Sangwoo, Jang, Yu-Sin, Ha, Sung-Chul, Ahn, Jae-Woo, Kim, Eun-Jung, Hong Lim, Jae, Cho, Changhee, Shin Ryu, Yong, Kuk Lee, Sung, Lee, Sang Yup, Kim, Kyung-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595758/ https://www.ncbi.nlm.nih.gov/pubmed/26391388 http://dx.doi.org/10.1038/ncomms9410 |
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