De novo assembly and next-generation sequencing to analyse full-length gene variants from codon-barcoded libraries

Interpreting epistatic interactions is crucial for understanding evolutionary dynamics of complex genetic systems and unveiling structure and function of genetic pathways. Although high resolution mapping of en masse variant libraries renders molecular biologists to address genotype-phenotype relati...

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Detalles Bibliográficos
Autores principales: Cho, Namjin, Hwang, Byungjin, Yoon, Jung-ki, Park, Sangun, Lee, Joongoo, Seo, Han Na, Lee, Jeewon, Huh, Sunghoon, Chung, Jinsoo, Bang, Duhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595759/
https://www.ncbi.nlm.nih.gov/pubmed/26387459
http://dx.doi.org/10.1038/ncomms9351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595759/
https://www.ncbi.nlm.nih.gov/pubmed/26387459
http://dx.doi.org/10.1038/ncomms9351

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