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De novo assembly and next-generation sequencing to analyse full-length gene variants from codon-barcoded libraries
Interpreting epistatic interactions is crucial for understanding evolutionary dynamics of complex genetic systems and unveiling structure and function of genetic pathways. Although high resolution mapping of en masse variant libraries renders molecular biologists to address genotype-phenotype relati...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595759/ https://www.ncbi.nlm.nih.gov/pubmed/26387459 http://dx.doi.org/10.1038/ncomms9351 |