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miR-34/449 control apical actin network formation during multiciliogenesis through small GTPase pathways

Vertebrate multiciliated cells (MCCs) contribute to fluid propulsion in several biological processes. We previously showed that microRNAs of the miR-34/449 family trigger MCC differentiation by repressing cell cycle genes and the Notch pathway. Here, using human and Xenopus MCCs, we show that beyond...

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Detalles Bibliográficos
Autores principales: Chevalier, Benoît, Adamiok, Anna, Mercey, Olivier, Revinski, Diego R., Zaragosi, Laure-Emmanuelle, Pasini, Andrea, Kodjabachian, Laurent, Barbry, Pascal, Marcet, Brice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595761/
https://www.ncbi.nlm.nih.gov/pubmed/26381333
http://dx.doi.org/10.1038/ncomms9386