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miR-34/449 control apical actin network formation during multiciliogenesis through small GTPase pathways
Vertebrate multiciliated cells (MCCs) contribute to fluid propulsion in several biological processes. We previously showed that microRNAs of the miR-34/449 family trigger MCC differentiation by repressing cell cycle genes and the Notch pathway. Here, using human and Xenopus MCCs, we show that beyond...
Autores principales: | Chevalier, Benoît, Adamiok, Anna, Mercey, Olivier, Revinski, Diego R., Zaragosi, Laure-Emmanuelle, Pasini, Andrea, Kodjabachian, Laurent, Barbry, Pascal, Marcet, Brice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595761/ https://www.ncbi.nlm.nih.gov/pubmed/26381333 http://dx.doi.org/10.1038/ncomms9386 |
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