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Plant-derived SAC domain of PAR-4 (Prostate Apoptosis Response 4) exhibits growth inhibitory effects in prostate cancer cells

The gene Par-4 (Prostate Apoptosis Response 4) was originally identified in prostate cancer cells undergoing apoptosis and its product Par-4 showed cancer specific pro-apoptotic activity. Particularly, the SAC domain of Par-4 (SAC-Par-4) selectively kills cancer cells leaving normal cells unaffected...

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Detalles Bibliográficos
Autores principales: Sarkar, Shayan, Jain, Sumeet, Rai, Vineeta, Sahoo, Dipak K., Raha, Sumita, Suklabaidya, Sujit, Senapati, Shantibhusan, Rangnekar, Vivek M., Maiti, Indu B., Dey, Nrisingha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595782/
https://www.ncbi.nlm.nih.gov/pubmed/26500666
http://dx.doi.org/10.3389/fpls.2015.00822