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Plant-derived SAC domain of PAR-4 (Prostate Apoptosis Response 4) exhibits growth inhibitory effects in prostate cancer cells
The gene Par-4 (Prostate Apoptosis Response 4) was originally identified in prostate cancer cells undergoing apoptosis and its product Par-4 showed cancer specific pro-apoptotic activity. Particularly, the SAC domain of Par-4 (SAC-Par-4) selectively kills cancer cells leaving normal cells unaffected...
Autores principales: | Sarkar, Shayan, Jain, Sumeet, Rai, Vineeta, Sahoo, Dipak K., Raha, Sumita, Suklabaidya, Sujit, Senapati, Shantibhusan, Rangnekar, Vivek M., Maiti, Indu B., Dey, Nrisingha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595782/ https://www.ncbi.nlm.nih.gov/pubmed/26500666 http://dx.doi.org/10.3389/fpls.2015.00822 |
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