Misfolded N-CoR is Linked to the Ectopic Reactivation of CD34/Flt3-Based Stem-Cell Phenotype in Promyelocytic and Monocytic Acute Myeloid Leukemia

Nuclear receptor co-repressor (N-CoR) is the key component of generic co-repressor complex essential for the transcriptional control of genes involved in cellular hemostasis. We have recently reported that N-CoR actively represses Flt3, a key factor of hematopoietic stem cells (HSC) self-renewal and...

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Detalles Bibliográficos
Autores principales: Nin, Dawn Sijin, Li, Feng, Visvanathan, Sridevi, Khan, Matiullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595783/
https://www.ncbi.nlm.nih.gov/pubmed/26500885
http://dx.doi.org/10.3389/fonc.2015.00210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595783/
https://www.ncbi.nlm.nih.gov/pubmed/26500885
http://dx.doi.org/10.3389/fonc.2015.00210

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