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A strategy to discover decoy chemokine ligands with an anti-inflammatory activity

Excessive signaling by chemokines has been associated with chronic inflammation or cancer, thus attracting substantial attention as promising therapeutic targets. Inspired by chemokine-clearing molecules shaped by pathogens to escape the immune system, we designed a generic screening assay to discov...

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Detalles Bibliográficos
Autores principales: Abboud, Dayana, Daubeuf, François, Do, Quoc Tuan, Utard, Valérie, Villa, Pascal, Haiech, Jacques, Bonnet, Dominique, Hibert, Marcel, Bernard, Philippe, Galzi, Jean-Luc, Frossard, Nelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595804/
https://www.ncbi.nlm.nih.gov/pubmed/26442456
http://dx.doi.org/10.1038/srep14746