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A note on the false discovery rate of novel peptides in proteogenomics

Motivation: Proteogenomics has been well accepted as a tool to discover novel genes. In most conventional proteogenomic studies, a global false discovery rate is used to filter out false positives for identifying credible novel peptides. However, it has been found that the actual level of false posi...

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Detalles Bibliográficos
Autores principales: Zhang, Kun, Fu, Yan, Zeng, Wen-Feng, He, Kun, Chi, Hao, Liu, Chao, Li, Yan-Chang, Gao, Yuan, Xu, Ping, He, Si-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595894/
https://www.ncbi.nlm.nih.gov/pubmed/26076724
http://dx.doi.org/10.1093/bioinformatics/btv340