HIV–tuberculosis-associated immune reconstitution inflammatory syndrome is characterized by Toll-like receptor and inflammasome signalling

Patients with HIV-associated tuberculosis (TB) initiating antiretroviral therapy (ART) may develop immune reconstitution inflammatory syndrome (TB-IRIS). No biomarkers for TB-IRIS have been identified and the underlying mechanisms are unclear. Here we perform transcriptomic profiling of the blood sa...

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Detalles Bibliográficos
Autores principales: Lai, Rachel P. J., Meintjes, Graeme, Wilkinson, Katalin A., Graham, Christine M., Marais, Suzaan, Van der Plas, Helen, Deffur, Armin, Schutz, Charlotte, Bloom, Chloe, Munagala, Indira, Anguiano, Esperanza, Goliath, Rene, Maartens, Gary, Banchereau, Jacques, Chaussabel, Damien, O'Garra, Anne, Wilkinson, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595995/
https://www.ncbi.nlm.nih.gov/pubmed/26399326
http://dx.doi.org/10.1038/ncomms9451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595995/
https://www.ncbi.nlm.nih.gov/pubmed/26399326
http://dx.doi.org/10.1038/ncomms9451

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