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Individual Cytokines Modulate the Neurological Symptoms of ATM Deficiency in a Region Specific Manner1,2,3
Ataxia-telangiectasia (A-T) is a multisystemic neurodegenerative disease of childhood caused by the absence of functional ATM (A-T mutated) protein. The cerebellar cortex has the most obvious neuropathology, yet cells in other brain regions are also abnormal. A-T mouse models have been produced that...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Society for Neuroscience
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596028/ https://www.ncbi.nlm.nih.gov/pubmed/26465009 http://dx.doi.org/10.1523/ENEURO.0032-15.2015 |