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Mechanisms Leading to Rhythm Cessation in the Respiratory PreBötzinger Complex Due to Piecewise Cumulative Neuronal Deletions1,2,3

The mammalian breathing rhythm putatively originates from Dbx1-derived interneurons in the preBötzinger complex (preBötC) of the ventral medulla. Cumulative deletion of ∼15% of Dbx1 preBötC neurons in an in vitro breathing model stops rhythmic bursts of respiratory-related motor output. Here we asse...

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Detalles Bibliográficos
Autores principales: Song, Hanbing, Hayes, John A., Vann, Nikolas C., Drew LaMar, M., Del Negro, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596029/
https://www.ncbi.nlm.nih.gov/pubmed/26465010
http://dx.doi.org/10.1523/ENEURO.0031-15.2015