Sex Steroids Do Not Modulate TRPM2-Mediated Injury in Females following Middle Cerebral Artery Occlusion(1,2,3)

Calcium-permeable transient receptor potential M2 (TRPM2) ion channel activation contributes to cerebral ischemic injury specifically in males. In male mice, circulating androgens are required for TRPM2 inhibition with clotrimazole (CTZ) to provide protection following experimental stroke. Sufficien...

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Detalles Bibliográficos
Autores principales: Quillinan, Nidia, Grewal, Himmat, Klawitter, Jelena, Herson, Paco S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2014
Materias:
Disorders of the Nervous System
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596140/
https://www.ncbi.nlm.nih.gov/pubmed/26464961
http://dx.doi.org/10.1523/ENEURO.0022-14.2014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596140/
https://www.ncbi.nlm.nih.gov/pubmed/26464961
http://dx.doi.org/10.1523/ENEURO.0022-14.2014

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