Transcytosis in the blood–cerebrospinal fluid barrier of the mouse brain with an engineered receptor/ligand system

Crossing the blood–brain and the blood–cerebrospinal fluid barriers (BCSFB) is one of the fundamental challenges in the development of new therapeutic molecules for brain disorders because these barriers prevent entry of most drugs from the blood into the brain. However, some large molecules, like t...

Descripción completa

Detalles Bibliográficos
Autores principales: Méndez-Gómez, Héctor R, Galera-Prat, Albert, Meyers, Craig, Chen, Weijun, Singh, Jasbir, Carrión-Vázquez, Mariano, Muzyczka, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596253/
https://www.ncbi.nlm.nih.gov/pubmed/26491705
http://dx.doi.org/10.1038/mtm.2015.37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596253/
https://www.ncbi.nlm.nih.gov/pubmed/26491705
http://dx.doi.org/10.1038/mtm.2015.37

Ejemplares similares