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Transcytosis in the blood–cerebrospinal fluid barrier of the mouse brain with an engineered receptor/ligand system
Crossing the blood–brain and the blood–cerebrospinal fluid barriers (BCSFB) is one of the fundamental challenges in the development of new therapeutic molecules for brain disorders because these barriers prevent entry of most drugs from the blood into the brain. However, some large molecules, like t...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596253/ https://www.ncbi.nlm.nih.gov/pubmed/26491705 http://dx.doi.org/10.1038/mtm.2015.37 |