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Role of endothelin receptor antagonist; bosentan in cisplatin-induced nephrotoxicity in ovariectomized estradiol treated rats

Background: Endothelin-1 (ET-1) is a vasoconstrictor peptide that mediates cell proliferation, fibrosis, and inflammation. ET-1 has 2 receptors A and B. Objectives: The present study investigated whether administration of ET-1 receptor type A antagonist leads to protect cisplatin (CP) induced nephro...

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Detalles Bibliográficos
Autores principales: Zahedi, Alieh, Nematbakhsh, Mehdi, Moeini, Maryam, Talebi, Ardeshir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Diabetic Nephropathy Prevention 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596298/
https://www.ncbi.nlm.nih.gov/pubmed/26457261
http://dx.doi.org/10.12860/jnp.2015.25