A new high-throughput screening-compatible gap junctional intercellular communication assay

BACKGROUND: Gap junctions (GJs) are intercellular channels through which molecules smaller than 1 kDa can diffuse, and they have been suggested as drug targets. To develop chemical drugs acting on this target, a high-throughput screening (HTS) system for GJ modulators is necessary. RESULTS: We desig...

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Detalles Bibliográficos
Autores principales: Lee, Ju Yeon, Choi, Eun Ju, Lee, Jinu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596302/
https://www.ncbi.nlm.nih.gov/pubmed/26444544
http://dx.doi.org/10.1186/s12896-015-0211-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596302/
https://www.ncbi.nlm.nih.gov/pubmed/26444544
http://dx.doi.org/10.1186/s12896-015-0211-3

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