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Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age

BACKGROUND: Chronic low-grade inflammation is considered a driver of many age-related disorders, including vascular diseases (inflammaging). Inhibition of autophagic capacity with ageing was postulated to generate a pro-inflammatory condition via activation of inflammasomes, a group of Interleukin-1...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoyu, Hakimi, Maani, Wortmann, Markus, Zhang, Jian, Böckler, Dittmar, Dihlmann, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596365/
https://www.ncbi.nlm.nih.gov/pubmed/26448778
http://dx.doi.org/10.1186/s12979-015-0043-y