Correction of Down syndrome and Edwards syndrome aneuploidies in human cell cultures

Aneuploidy, an abnormal number of chromosomes, has previously been considered irremediable. Here, we report findings that euploid cells increased among cultured aneuploid cells after exposure to the protein ZSCAN4, encoded by a mammalian-specific gene that is ordinarily expressed in preimplantation...

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Detalles Bibliográficos
Autores principales: Amano, Tomokazu, Jeffries, Emiko, Amano, Misa, Ko, Akihiro C., Yu, Hong, Ko, Minoru S. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596399/
https://www.ncbi.nlm.nih.gov/pubmed/26324424
http://dx.doi.org/10.1093/dnares/dsv016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596399/
https://www.ncbi.nlm.nih.gov/pubmed/26324424
http://dx.doi.org/10.1093/dnares/dsv016

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