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Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4+ T cells in aged rats

BACKGROUND: Aging influences immune response and susceptibility to EAE in a strain specific manner. The study was designed to examine influence of aging on EAE induction in Albino Oxford (AO) rats. RESULTS: Differently from 3-month-old (young) rats, which were resistant to EAE induction, the majorit...

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Detalles Bibliográficos
Autores principales: Stojić-Vukanić, Zorica, Nacka-Aleksić, Mirjana, Pilipović, Ivan, Vujnović, Ivana, Blagojević, Veljko, Kosec, Duško, Dimitrijević, Mirjana, Leposavić, Gordana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596406/
https://www.ncbi.nlm.nih.gov/pubmed/26448779
http://dx.doi.org/10.1186/s12979-015-0044-x