Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia

BACKGROUND: Haemoglobin S (HbS) is the gene known to confer the strongest advantage against malaria morbidity and mortality. Multiple HbS effects have been described resulting in protection against parasitaemia and reduction of severe malaria risk. This study aimed to explore HbS protection against...

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Detalles Bibliográficos
Autores principales: do Sambo, Maria Rosário, Penha-Gonçalves, Carlos, Trovoada, Maria Jesus, Costa, João, Lardoeyt, Roberto, Coutinho, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596417/
https://www.ncbi.nlm.nih.gov/pubmed/26445879
http://dx.doi.org/10.1186/s12936-015-0920-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596417/
https://www.ncbi.nlm.nih.gov/pubmed/26445879
http://dx.doi.org/10.1186/s12936-015-0920-z

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